Article
Position-effect variegation in Drosophila depends on dose of the gene encoding the E2F transcriptional activator and cell cycle regulator.
Development (Cambridge, England) - 1 Jun 1996
Seum C, Spierer A, Pauli D, Szidonya J, Reuter G, Spierer P
Abstract excerpt
A dominant mutation due to the insertion of a P-element at 93E on the third chromosome of Drosophila melanogaster enhances position-effect variegation. The corresponding gene was cloned by transposon tagging and the sequence of the transcript revealed that it corresponds to the gene encoding the...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cell Cycle Proteins
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- E2F Transcription Factors
- Enhancer Elements, Genetic
- Eye Color
- Female
- Gene Dosage
- Gene Expression Regulation
- Insect Hormones
- Male