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Article

Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila.

Cell - 5 Oct 1990

Karpen G H, Spradling A C

Abstract excerpt

Molecular analysis of a Drosophila minichromosome, Dp(1;f)1187, revealed a relationship between position-effect variegation and the copy number reductions of heterochromatic sequences that occur in polytene cells. Heterochromatin adjacent to a defined junction with euchromatin underpolytenized at least 60-fold. Lesser reductions were observed in euchromatic sequences up to 103 kb from the breakpoint. The copy...

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Identifiers

PMID: 2208283
DOI: 10.1016/0092-8674(90)90291-l
PMCID: PMC3229194

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