Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila.

doi:10.1016/0092-8674(90)90291-l

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Article

Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila.

Cell - 5 Oct 1990

Karpen G H, Spradling A C

Abstract excerpt

Molecular analysis of a Drosophila minichromosome, Dp(1;f)1187, revealed a relationship between position-effect variegation and the copy number reductions of heterochromatic sequences that occur in polytene cells. Heterochromatin adjacent to a defined junction with euchromatin underpolytenized at...

Topics

Animals
Chromosome Deletion
Chromosome Mapping
DNA
Drosophila
Female
Heterochromatin
Male
Mutation
Nucleic Acid Hybridization
Restriction Mapping
Salivary Glands

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