Article
A high proportion of genes involved in position effect variegation also affect chromosome inheritance.
Chromosoma - 1 Mar 2004
Le Hiep D, Donaldson Kathryn M, Cook Kevin R, Karpen Gary H
Abstract excerpt
Suppressors and enhancers of position effect variegation (PEV) have been linked to the establishment and maintenance of heterochromatin. The presence of centromeres and other inheritance elements in heterochromatic regions suggests that suppressors and enhancers of PEV, Su(var) s and E(var)s [collectively termed Mod(var)s], may be required for chromosome inheritance. In order to test this hypothesis, we screened...
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