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Article

Immunoglobulin genes in chronic lymphocytic leukemia: key to understanding the disease and improving risk stratification

31 May 2017

Abstract excerpt

While triggering through the B-cell receptor (BcR) facilitates B-cell development and maintenance, it also carries intertwined risks for the emergence of lymphoid malignancies, since malignant B cells can exploit BcR signaling pathways in order to initiate and fuel clonal expansion. Indeed,

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Identifiers

PMID: 28566340
DOI: 10.3324/haematol.2017.165605

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