Article
Variants of CEP68 gene are associated with acute urticaria/angioedema induced by multiple non-steroidal anti-inflammatory drugs.
PloS one - 1 Jan 2014
Cornejo-García José Antonio, Flores Carlos, Plaza-Serón María C, Acosta-Herrera Marialbert, Blanca-López Natalia, Doña Inmaculada, Torres María J, Mayorga Cristobalina, Guéant-Rodríguez Rosa M, Ayuso Pedro, Fernández Javier, Laguna José J, Agúndez José A G, García-Martín Elena, Guéant Jean-Louis, Canto Gabriela, Blanca Miguel
Abstract excerpt
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most consumed drugs worldwide because of their efficacy and utility in the treatment of pain and inflammatory diseases. However, they are also responsible for an important number of adverse effects including hypersensitivity reactions. The most important group of these reactions is triggered by non-immunological, pharmacological mechanisms catalogued under...
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