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Article

The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain.

Nucleic acids research - 1 Mar 2011

Yeeles Joseph T P, Gwynn Emma J, Webb Martin R, Dillingham Mark S

Abstract excerpt

The oligomeric state of Superfamily I DNA helicases is the subject of considerable and ongoing debate. While models based on crystal structures imply that a single helicase core domain is sufficient for DNA unwinding activity, biochemical data from several related enzymes suggest that a higher order oligomeric species is required. In this work we characterize the helicase activity of the AddAB helicase-nuclease,...

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Identifiers

PMID: 21071401
DOI: 10.1093/nar/gkq1124
PMCID: PMC3064778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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