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Article

Homologous recombination mediated by the mycobacterial AdnAB helicase without end resection by the AdnAB nucleases.

Nucleic acids research - 25 Jan 2017

Gupta Richa, Unciuleac Mihaela-Carmen, Shuman Stewart, Glickman Michael S

Abstract excerpt

Current models of bacterial homologous recombination (HR) posit that extensive resection of a DNA double-strand break (DSB) by a multisubunit helicase-nuclease machine (e.g. RecBCD, AddAB or AdnAB) generates the requisite 3' single-strand DNA substrate for RecA-mediated strand invasion. AdnAB, the helicase-nuclease implicated in mycobacterial HR, consists of two subunits, AdnA and AdnB, each composed of an...

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Identifiers

PMID: 27899634
DOI: 10.1093/nar/gkw1130
PMCID: PMC5314763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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