Article
An essential DnaB helicase of Bacillus anthracis: identification, characterization, and mechanism of action.
Journal of bacteriology - 1 Jan 2009
Biswas Esther E, Barnes Marjorie H, Moir Donald T, Biswas Subhasis B
Abstract excerpt
We have described a novel essential replicative DNA helicase from Bacillus anthracis, the identification of its gene, and the elucidation of its enzymatic characteristics. Anthrax DnaB helicase (DnaB(BA)) is a 453-amino-acid, 50-kDa polypeptide with ATPase and DNA helicase activities. DnaB(BA) displayed distinct enzymatic and kinetic properties. DnaB(BA) has low single-stranded DNA (ssDNA)-dependent ATPase...
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