Article
The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1 helicase-like motor.
Nucleic acids research - 16 Mar 2018
Toliusis Paulius, Tamulaitiene Giedre, Grigaitis Rokas, Tuminauskaite Donata, Silanskas Arunas, Manakova Elena, Venclovas Ceslovas, Szczelkun Mark D, Siksnys Virginijus, Zaremba Mindaugas
Abstract excerpt
CglI is a restriction endonuclease from Corynebacterium glutamicum that forms a complex between: two R-subunits that have site specific-recognition and nuclease domains; and two H-subunits, with Superfamily 2 helicase-like DEAD domains, and uncharacterized Z1 and C-terminal domains. ATP hydrolysis by the H-subunits catalyses dsDNA translocation that is necessary for long-range movement along DNA that activates...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.