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Article

AdnAB: a new DSB-resecting motor-nuclease from mycobacteria.

Genes & development - 15 Jun 2009

Sinha Krishna Murari, Unciuleac Mihaela-Carmen, Glickman Michael S, Shuman Stewart

Abstract excerpt

The resection of DNA double-strand breaks (DSBs) in bacteria is a motor-driven process performed by a multisubunit helicase-nuclease complex: either an Escherichia coli-type RecBCD enzyme or a Bacillus-type AddAB enzyme. Here we identify mycobacterial AdnAB as the founder of a new family of heterodimeric helicase-nucleases with distinctive properties. The AdnA and AdnB subunits are each composed of an N-terminal...

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Identifiers

PMID: 19470566
DOI: 10.1101/gad.1805709
PMCID: PMC2701575

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Source receipt: pubmed, retrieved 7 Sept 2026.

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