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Article

Influence of the type of F8 gene mutation on inhibitor development in a single centre cohort of severe haemophilia A patients.

Haemophilia : the official journal of the World Federation of Hemophilia - 1 Mar 2011

Gouw S C, Van Der Bom J G, Van Den Berg H M, Zewald R A, Ploos Van Amstel J K, Mauser-Bunschoten E P

Abstract excerpt

The development of neutralizing antibodies against factor VIII (FVIII) is a major complication of treatment with FVIII in patients with severe haemophilia A. This study was designed to describe the relationship between the type and location of the factor 8 (F8) gene mutation and the development of clinically relevant inhibitors in patients with severe haemophilia A. We conducted a single centre cohort study among...

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Identifiers

PMID: 21070499
DOI: 10.1111/j.1365-2516.2010.02420.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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