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Article

The Italian AICE-Genetics hemophilia A database: results and correlation with clinical phenotype.

Haematologica - 1 May 2008

Margaglione Maurizio, Castaman Giancarlo, Morfini Massimo, Rocino Angiola, Santagostino Elena, Tagariello Giuseppe, Tagliaferri Anna Rita, Zanon Ezio, Bicocchi Maria Patrizia, Castaldo Giuseppe, Peyvandi Flora, Santacroce Rosa, Torricelli Francesca, Grandone Elvira, Mannucci Pier Mannuccio

Abstract excerpt

BACKGROUND: The high mutational heterogeneity of hemophilia A is a challenge for the provision of genetic services. We plan to identify the mutation in patients with hemophilia A in order to create a confidential national database of mutations for the optimization of genetic services in Italy. DESIGN AND METHODS: The factor VIII gene (F8) was analyzed in 1296 unrelated patients with hemophilia A using screening...

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PMID: 18387975
DOI: 10.3324/haematol.12427

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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