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Article

Factor VIII (FVIII) gene mutations in 120 patients with hemophilia A: detection of 26 novel mutations and correlation with FVIII inhibitor development.

Journal of thrombosis and haemostasis : JTH - 1 Jul 2007

Repessé Y, Slaoui M, Ferrandiz D, Gautier P, Costa C, Costa J M, Lavergne J M, Borel-Derlon A

Abstract excerpt

BACKGROUND: As the publication of the sequence of the factor VIII gene (FVIII) in 1984, a large number of mutations that cause hemophilia A (HA) have been identified. Thanks to the advances in the detection of mutations, it is now possible to identify a putative FVIII sequence alteration in the vast majority of patients with HA. OBJECTIVES: Our main objective was to report on the spectrum of FVIII mutations and...

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PMID: 17445092
DOI: 10.1111/j.1538-7836.2007.02591.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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