Article
Biochemical defects of mutant nudel alleles causing early developmental arrest or dorsalization of the Drosophila embryo.
Genetics - 1 Jan 2000
LeMosy E K, Leclerc C L, Hashimoto C
Abstract excerpt
The nudel gene of Drosophila is maternally required both for structural integrity of the egg and for dorsoventral patterning of the embryo. It encodes a structurally modular protein that is secreted by ovarian follicle cells. Genetic and molecular studies have suggested that the Nudel protein is also functionally modular, with a serine protease domain that is specifically required for ventral development. Here we...
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