Article
Lupus nephritis in the absence of renal major histocompatibility complex class I and class II molecules.
Journal of the American Society of Nephrology : JASN - 1 Nov 1996
Mukherjee R, Zhang Z, Zhong R, Yin Z Q, Roopenian D C, Jevnikar A M
Abstract excerpt
MRL/Mp-lpr/lpr (MRL-lpr) mice develop an aggressive autoimmune disorder characterized by arthritis, vasculitis, and glomerulonephritis. Renal injury is associated with increased expression of major histocompatibility complex (MHC) molecules, as well as cytokines, adhesion molecules (intracellular...
Topics
- Animals
- Antibodies, Anti-Idiotypic
- Antibodies, Antinuclear
- Cell Division
- Cells, Cultured
- Female
- Follow-Up Studies
- Gene Deletion
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Immunoglobulin G
- Immunoglobulin M
- Kidney Transplantation
- Lupus Nephritis
- Male
- Mice
- Mice, Inbred MRL lpr
- Phenotype