Article
Glycophorin C delta(exon3) is not associated with protection against severe anaemia in Papua New Guinea.
Papua and New Guinea medical journal - 1 Jan 2000
Tavul L, Mueller I, Rare L, Lin E, Zimmerman P A, Reeder J, Siba P, Michon P
Abstract excerpt
The high frequencies of mutant haemoglobin and erythrocyte surface proteins in malaria-endemic regions have indicated that polymorphisms in human genes have been under selection pressure by severe malarial disease. Glycophorin C (GYPC) is a major surface erythrocyte protein and also a receptor for the Plasmodium falciparum erythrocyte-binding antigen 140 (EBA-140, also known as BAEBL). There is no binding to GYPC...
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