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Article

A single-step assay for the Gerbich-negative allele of glycophorin C.

Blood cells, molecules & diseases - 1 Jan 2000

Scott Brendan, Easteal Simon

Abstract excerpt

The Gerbich erythrocyte surface protein, glycophorin C (GYPC), can be used by Plasmodium falciparum to invade erythrocytes. The Melanesian Gerbich-negative antigenic condition (Ge(-)) is frequent in some populations where malaria is endemic, suggesting that it protects against malaria. We have determined as precisely as possible the breakpoint of the chromosomal deletion that causes the Ge(-) condition by...

Topics

Alleles
Animals
Base Sequence
Erythrocyte Membrane
Exons
Genetic Predisposition to Disease
Genotype
Glycophorins
Humans
Malaria, Falciparum
Molecular Sequence Data
Plasmodium falciparum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Sequence Alignment

Source

Identifiers

PMID: 18407531
DOI: 10.1016/j.bcmd.2008.02.009

Genes

GYPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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A single-step assay for the Gerbich-negative allele of glycophorin C.PMID 18407531Read ↗

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