A 3.5 kb deletion in the glycophorin C gene accounts for the Gerbich-negative blood group in Melanesians.

doi:10.1038/icb.1994.4

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Article

A 3.5 kb deletion in the glycophorin C gene accounts for the Gerbich-negative blood group in Melanesians.

Immunology and cell biology - 1 Feb 1994

Serjeantson S W, White B S, Bhatia K, Trent R J

Abstract excerpt

The Gerbich-negative blood group types are rare in most populations, but reach appreciable frequencies in certain Melanesian groups in Papua New Guinea. The recent cloning of the human glycophorin C (GPC) gene, that encodes Gerbich (Ge) blood group antigens, has facilitated study of its genetic v...

Topics

Anion Exchange Protein 1, Erythrocyte
Blood Group Antigens
Blotting, Southern
DNA
Elliptocytosis, Hereditary
Erythrocytes
Female
Gene Deletion
Genotype
Glycophorins
Humans
Male
Melanesia
Molecular Weight
Pedigree
Phenotype
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8157284
DOI: 10.1038/icb.1994.4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8157284-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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