Article
Minimal association of common red blood cell polymorphisms with Plasmodium falciparum infection and uncomplicated malaria in Papua New Guinean school children.
The American journal of tropical medicine and hygiene - 1 Oct 2010
Lin Enmoore, Tavul Livingstone, Michon Pascal, Richards Jack S, Dabod Elijah, Beeson James G, King Christopher L, Zimmerman Peter A, Mueller Ivo
Abstract excerpt
Southeast Asian ovalocytosis (SAO), α(+)-thalassemia, and low expression of complement receptor 1 (CR1) have been associated with protection against severe Plasmodium falciparum malaria. In a cohort of children 5-14 years of age the effect of α(+)-thalassemia, SAO (SLC4A1Δ27), CR1 polymorphisms, and Gerbich negativity (GYPCΔex3) on risk of P. falciparum infections and uncomplicated illness were evaluated. The...
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