Article
Glycophorin C (Gerbich antigen blood group) and band 3 polymorphisms in two malaria holoendemic regions of Papua New Guinea.
American journal of hematology - 1 Jan 2004
Patel Sheral S, King Christopher L, Mgone Charles S, Kazura James W, Zimmerman Peter A
Abstract excerpt
The geographic overlap between the prevalence of erythrocyte polymorphisms and malaria endemicity is thought to be an example of natural selection on human populations. In Papua New Guinea (PNG), the Gerbich-negative phenotype is caused by an exon 3 deletion in the glycophorin C gene (GYPCDeltaex3) while heterozygosity for a 27-base pair deletion in the SLC4A1 gene (anion exchanger 1 or erythrocyte membrane...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
