A Very Bright Far-Red Bioluminescence Emitting Combination Based on Engineered Railroad Worm Luciferase and 6'-Amino-Analogs for Bioimaging Purposes.

doi:10.3390/ijms22010303

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Article

A Very Bright Far-Red Bioluminescence Emitting Combination Based on Engineered Railroad Worm Luciferase and 6'-Amino-Analogs for Bioimaging Purposes.

International journal of molecular sciences - 30 Dec 2020

Viviani Vadim R, Bevilaqua Vanessa R, de Souza Daniel R, Pelentir Gabriel F, Kakiuchi Michio, Hirano Takashi

Abstract excerpt

Beetle luciferases produce bioluminescence (BL) colors ranging from green to red, having been extensively used for many bioanalytical purposes, including bioimaging of pathogen infections and metastasis proliferation in living animal models and cell culture. For bioimaging purposes in mammalian tissues, red bioluminescence is preferred, due to the lower self-absorption of light at longer wavelengths by...

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PMID: 33396708
DOI: 10.3390/ijms22010303
PMCID: PMC7794784

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