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Article

Pandemic H1N1 influenza A infection and (atypical) HUS--more than just another trigger?

Pediatric nephrology (Berlin, Germany) - 1 Jan 2011

Allen Upton, Licht Christoph

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is caused by mutations resulting in an exceedingly active alternative complement pathway. While today more than half a dozen genes are involved in aHUS pathology, only about 50% of carriers precipitate the disease. The reason for this phenomenon remains unclear, and triggering events like intercurrent infections have been postulated. In this context, reports on the...

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PMID: 21057815
DOI: 10.1007/s00467-010-1690-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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