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Article

Autoantibodies in haemolytic uraemic syndrome (HUS).

Thrombosis and haemostasis - 1 Feb 2009

Skerka Christine, Józsi Mihály, Zipfel Peter F, Dragon-Durey Marie-Agnes, Fremeaux-Bacchi Veronique

Abstract excerpt

Haemolytic uraemic syndrome (HUS) is a severe disease with renal failure, microangiopathic anemia and thrombocytopenia. Several mechanisms leading to HUS have been identified, like infections with enterohaemorrhagic Escherichia coli, as well as genetic mutations of complement genes, which result in defective complement control on the surface of host cells. The complement system forms the first defense line of...

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Share to Autoantibodies
Share to Blood Proteins
Share to Complement Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibody Specificity

Share to Complement C3b Inactivator Proteins

Share to Complement Factor H

Share to Hemolytic-Uremic Syndrome

Share to Immunity, Innate

Source

Identifiers

PMID: 19190803

Genes

CFHR1
CFHR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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