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Article

Polymorphisms in methylenetetrahydrofolate reductase gene and risk of non-Hodgkin lymphoma in a multi-ethnic population.

Journal of human genetics - 1 May 2014

Suthandiram Sujatha, Gan Gin Gin, Zain Shamsul Mohd, Haerian Batoul Sadat, Bee Ping Chong, Lian Lay Hoong, Chang Kian Meng, Ong Tee Chuan, Mohamed Zahurin

Abstract excerpt

An imbalance in folate metabolism can adversely affect DNA synthesis and methylation systems which can lead to susceptibility to non-Hodgkin lymphoma (NHL). Whether single nucleotide polymorphisms (SNPs) and their haplotypes in the methylenetetrahydrofolate reductase (MTHFR) are associated with NHL, remain inconclusive. We investigated the association between MTHFR C677T and A1298C SNPs and NHL risk in a...

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PMID: 24646728
DOI: 10.1038/jhg.2014.19

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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