Article
Neuropeptide Y-Y2 receptor knockout mice: influence of genetic background on anxiety-related behaviors.
Neuroscience - 10 Mar 2011
Zambello E, Zanetti L, Hédou G F, Angelici O, Arban R, Tasan R O, Sperk G, Caberlotto L
Abstract excerpt
Neuropeptide Y (NPY) has been extensively studied in relation to anxiety and depression but of the seven NPY receptors known to date, it is not yet clear which one is mainly involved in mediating its effects in emotional behavior. Mice lacking the NPY-Y2 receptors were previously shown to be less anxious due to their improved ability to cope with stressful situations. In the present study, the behavioral...
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