Article
Emotional behavior in aged neuropeptide Y (NPY) Y2 knockout mice.
Journal of molecular neuroscience : MN - 1 Jan 2006
Carvajal Cristina, Dumont Yvan, Herzog Herbert, Quirion Rémi
Abstract excerpt
Neuropeptide Y (NPY) was shown to modulate anxiety- and depression-related behaviors in various animal models. Previous studies demonstrated that NPY Y2 receptor knockout (KO) mice display an anxiolytic- and antidepressant-like phenotype compared with control animals. However, the long-term effect of the deletion of this receptor in aged animals is unknown. Thus, anxiety- and depression-related behaviors were...
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