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Article

Targeted mutation of CCK(2) receptor gene antagonises behavioural changes induced by social isolation in female, but not in male mice.

Behavioural brain research - 5 Nov 2004

Abramov Urho, Raud Sirli, Kõks Sulev, Innos Jürgen, Kurrikoff Kaido, Matsui Toshimitsu, Vasar Eero

Abstract excerpt

Neuropeptide cholecystokinin (CCK) regulates the adaptation of rodents in the novel environment. In the present study we analysed the behavioural changes induced by the individual housing in mice, lacking CCK(2) receptors. The wild-type (+/+) and homozygous (-/-) CCK(2) receptor deficient mice of both gender were used throughout the study. The weight gain during the 21-day isolation period and changes in the...

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Source

Identifiers

PMID: 15325774
DOI: 10.1016/j.bbr.2004.03.027

Genes

CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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