Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels.

doi:10.1038/343536a0

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Article

Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels.

Nature - 8 Feb 1990

Hardin P E, Hall J C, Rosbash M

Abstract excerpt

Mutations in the period (per) gene of Drosophila melanogaster affect both circadian and ultradian rhythms. Levels of per gene product undergo circadian oscillation, and it is now shown that there is an underlying oscillation in the level of per RNA. The observations indicate that the cycling of p...

Topics

Animals
Circadian Rhythm
Drosophila Proteins
Drosophila melanogaster
Feedback
Gene Expression Regulation
Motor Activity
Mutation
Nuclear Proteins
Period Circadian Proteins
Proteins
RNA, Messenger
Ribonucleases

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