Article
Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America - 9 Jul 2002
Lin Yiing, Han Mei, Shimada Brian, Wang Lin, Gibler Therese M, Amarakone Aloka, Awad Tarif A, Stormo Gary D, Van Gelder Russell N, Taghert Paul H
Abstract excerpt
We measured daily gene expression in heads of control and period mutant Drosophila by using oligonucleotide microarrays. In control flies, 72 genes showed diurnal rhythms in light-dark cycles; 22 of these also oscillated in free-running conditions. The period gene significantly influenced the expression levels of over 600 nonoscillating transcripts. Expression levels of several hundred genes also differed...
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