Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock.

doi:10.1038/326390a0

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Article

Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock.

Nature - 1 Jan 2000

Baylies M K, Bargiello T A, Jackson F R, Young M W

Abstract excerpt

The period (per) locus, which controls biological rhythms in Drosophila, was originally defined by three chemically induced mutations. Flies carrying the pero mutation were arrhythmic, whereas pers and perl mutants had circadian behavioural rhythms with 19-hour and 29-hour periodicities, respecti...

Topics

Amino Acid Sequence
Animals
Base Sequence
Circadian Rhythm
DNA
Drosophila melanogaster
Female
Mutation
Proteins
RNA
Transcription, Genetic
Transformation, Genetic

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