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Article

Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study.

Urologia internationalis - 1 Jan 2011

vom Dorp Frank, Sanders Harald, Boergermann Christof, Lümmen Gerd, Rübben Herbert, Jakobs Karl H, Schmidt Martina

Abstract excerpt

INTRODUCTION: Migration of cells involves a complex signaling network. The aim of the present study was to elucidate the impact of Rho-kinase (ROK) on G protein-coupled receptor-induced migration of human transitional cell carcinoma cells in an in vitro experimental setting. MATERIALS AND METHODS: Intracellular calcium concentration ([Ca(2+)](i)) was measured with the indicator dye Fura-2 in response to...

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PMID: 21051874
DOI: 10.1159/000321271

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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