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Article

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.

Cardiovascular research - 1 Mar 2011

Olesen Morten S, Jespersen Thomas, Nielsen Jonas B, Liang Bo, Møller Daniel V, Hedley Paula, Christiansen Michael, Varró András, Olesen Søren-Peter, Haunsø Stig, Schmitt Nicole, Svendsen Jesper H

Abstract excerpt

AIMS: Atrial fibrillation (AF) is the most frequent arrhythmia. Screening of SCN5A-the gene encoding the α-subunit of the cardiac sodium channel-has indicated that disturbances of the sodium current may play a central role in the mechanism of lone AF. We tested the hypothesis that lone AF in young patients is associated with genetic mutations in SCN3B and SCN4B, the genes encoding the two β-subunits of the...

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Identifiers

PMID: 21051419
DOI: 10.1093/cvr/cvq348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.PMID 21051419Read ↗

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