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Article

Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation.

Heart rhythm - 1 Feb 2014

Olesen Morten S, Andreasen Laura, Jabbari Javad, Refsgaard Lena, Haunsø Stig, Olesen Søren-Peter, Nielsen Jonas B, Schmitt Nicole, Svendsen Jesper H

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Currently, 14 genes important for ion channel function, intercellular signaling, and homeostatic control have been associated with AF. OBJECTIVE: We hypothesized that rare genetic variants in genes previously associated with AF had a higher prevalence in early-onset lone AF patients than in the background population. METHODS: Sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24144883
DOI: 10.1016/j.hrthm.2013.10.034

Genes

GJA5
KCNA5
KCND3
KCNH2
KCNJ2
KCNQ1
NPPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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