Article
A variant binding sequence for transcription factor EBP-80 confers increased promoter activity on a retroviral long terminal repeat.
The Journal of biological chemistry - 5 Aug 1990
Falzon M, Kuff E L
Abstract excerpt
The cloned long terminal repeats (LTRs) of mouse intracisternal A-particle (IAP) proviral elements differ in their promoter activity. In this study, the LTR from a recently transposed IAP element (rc-mos) is shown to be a more effective promoter both in vivo and in vitro than the LTR from a randomly cloned genomic element (MIA14). These LTRs differ in nucleotide sequence in certain previously defined...
Topics
- Animals
- Base Sequence
- Cell Line
- Cell Nucleus
- Chloramphenicol O-Acetyltransferase
- Cloning, Molecular
- DNA Transposable Elements
- Genetic Variation
- HeLa Cells
- Humans
- Kinetics
