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Article

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.

Molecular and cellular biology - 1 Jan 1992

Wang S W, Speck N A

Abstract excerpt

The Moloney murine leukemia virus causes thymic leukemias when injected into newborn mice. A major genetic determinant of the thymic disease specificity of the Moloney virus genetically maps to two protein binding sites in the Moloney virus enhancer, the leukemia virus factor b site and the adjacent core site. Point mutations introduced into either of these sites significantly shifts the disease specificity of...

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Identifiers

PMID: 1309596
DOI: 10.1128/mcb.12.1.89-102.1992
PMCID: PMC364072

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Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.PMID 1309596Read ↗

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