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Article

Nucleotide excision repair gene polymorphisms may predict acute toxicity in patients treated with chemoradiotherapy for bladder cancer.

Pharmacogenomics - 1 Oct 2010

Sakano Shigeru, Hinoda Yuji, Sasaki Miwa, Wada Takashi, Matsumoto Hiroaki, Eguchi Satoshi, Shinohara Asano, Kawai Yoshihisa, Hara Tomohiko, Nagao Kazuhiro, Hara Takahiko, Naito Katsusuke, Matsuyama Hideyasu

Abstract excerpt

AIMS: Platinum-based chemoradiotherapy (CRT) as bladder conservation therapy has shown promising results for muscle-invasive bladder cancer. However, treatment-related toxicity remains a major consideration in therapeutic planning. Some common polymorphisms in genes involved in DNA repair (encodi...

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Identifiers

PMID: 21047201
DOI: 10.2217/pgs.10.106

Genes

XPC
MDM2
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21047201-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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