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Article

Polymorphisms in the XRCC1 gene modify survival of bladder cancer patients treated with chemotherapy.

International journal of cancer - 15 Oct 2013

Sacerdote Carlotta, Guarrera Simonetta, Ricceri Fulvio, Pardini Barbara, Polidoro Silvia, Allione Alessandra, Critelli Rossana, Russo Alessia, Andrew Angeline S, Ye Yuanqing, Wu Xifeng, Kiemeney Lambertus A, Bosio Andrea, Casetta Giovanni, Cucchiarale Giuseppina, Destefanis Paolo, Gontero Paolo, Rolle Luigi, Zitella Andrea, Fontana Dario, Vineis Paolo, Matullo Giuseppe

Abstract excerpt

Survival of bladder cancer patients depends on several factors including disease stage and grade at diagnosis, age, health status of the patient and the applied treatment. Several studies investigated the role of DNA repair genetic variants in cancer susceptibility, but only few studies investigated their role in survival and response to chemotherapy for bladder cancer. We genotyped 28 single nucleotide...

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Identifiers

PMID: 23553206
DOI: 10.1002/ijc.28186
PMCID: PMC3804126

Genes

XRCC1

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