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Article

Polymorphisms in XPD gene could predict clinical outcome of platinum-based chemotherapy for non-small cell lung cancer patients: a meta-analysis of 24 studies.

PloS one - 1 Jan 2013

Qin Qin, Zhang Chi, Yang Xi, Zhu Hongcheng, Yang Baixia, Cai Jing, Cheng Hongyan, Ma Jianxin, Lu Jing, Zhan Liangliang, Liu Jia, Liu Zheming, Xu Liping, Sun Xinchen

Abstract excerpt

OBJECTIVE: Xeroderma pigmentosum group D (XPD) is an essential gene involved in the nucleotide excision repair (NER) pathway. Two commonly studied single nucleotide polymorphisms (SNPs) of XPD (Lys751Gln, A>C, rs13181; Asp312Asn, G>A, rs1799793) are implicated in the modulation of DNA repair capacity, thus related to the responses to platinum-based chemotherapy. Here we performed a meta-analysis to better...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antineoplastic Agents
Share to Carcinoma, Non-Small-Cell Lung
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Identifiers

PMID: 24260311
DOI: 10.1371/journal.pone.0079864
PMCID: PMC3829883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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