Article
Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy.
Pharmacogenomics - 1 Dec 2011
Giovannetti Elisa, Pacetti Paola, Reni Michele, Leon Leticia G, Mambrini Andrea, Vasile Enrico, Ghidini Michele, Funel Niccola, Lucchesi Matteo, Cereda Stefano, Peters Godefridus J, Cantore Maurizio
Abstract excerpt
AIM: This multicenter study evaluated the association of 11 candidate polymorphisms in eight genes with outcome of pancreatic cancer patients treated with the equivalent polychemotherapeutic regimens: cisplatin/epirubicin/capecitabine/gemcitabine, cisplatin/docetaxel/capecitabine/gemcitabine and gemcitabine/capecitabine plus epirubicin/cisplatin intra-arterial infusion. PATIENTS & METHODS: Towards this end,...
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