Article
A program for selecting DNA fragments to detect mutations by denaturing gel electrophoresis methods.
Nucleic acids research - 11 Oct 1994
Brossette S, Wartell R M
Abstract excerpt
A computer program was developed to automate the selection of DNA fragments for detecting mutations within a long DNA sequence by denaturing gel electrophoresis methods. The program, MELTSCAN, scans through a user specified DNA sequence calculating the melting behavior of overlapping DNA fragment...
Topics
- Algorithms
- Base Composition
- Codon
- DNA
- DNA, Complementary
- Electrophoresis, Polyacrylamide Gel
- Genes, p53
- Hot Temperature
- Mutation
- Nucleic Acid Denaturation
- Sequence Analysis, DNA
- Software
