Article
Rapid heteroduplex analysis by capillary electrophoresis.
Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2005
Kozlowski Piotr, Olejniczak Marta, Krzyzosiak Wlodzimierz J
Abstract excerpt
The very important parameters for mutation screening are short time of analysis and high throughput. The analytical platform which fulfills these criteria most satisfactorily is capillary electrophoresis. Here we show the influence of several parameters such as temperature, presence of glycerol, capillary length and polymer concentration on the electrophoretic properties of DNA duplexes and evaluate their...
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