Article
Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis.
Electrophoresis - 1 Jan 2003
Bjørheim Jens, Gaudernack Gustav, Giercksky Karl-Erik, Ekstrøm Per O
Abstract excerpt
Over the past few decades, advances in genetics and molecular biology have revolutionized our understanding of cancer initiation and progression. Molecular progression models outlining genetic events have been developed for many solid tumors, including colon cancer. Previous reports in the literature have shown a relationship between different KRAS mutations and prognosis and response to medical treatment in...
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