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Article

Notch Signaling Pathway as a Therapeutic Target in Breast Cancer

23 Oct 2010

Abstract excerpt

The highly conserved Notch signaling pathway is involved in regulating a number of key cellular processes. This pathway has been implicated in both the development and progression of breast cancer and has emerged as a possible therapeutic target. Several clinical trials are currently underway to determine if targeting the Notch pathway with drugs such as the γ-secretase inhibitors may be an effective therapeutic...

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PMID: 20971825
DOI: 10.1158/1535-7163.mct-10-0677

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