Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitor

12 May 2008

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Chemical Synthesis and Analysis
Share to HER2/EGFR in Cancer Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18469855
DOI: 10.1038/onc.2008.149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a γ-secretase inhibitorPMID 18469855Read ↗

NOTCH3 Signaling Pathway Plays Crucial Roles in the Proliferation of ErbB2-Negative Human Breast Cancer CellsSemantic proximity Read ↗

Notch Signaling Pathway as a Therapeutic Target in Breast CancerSemantic proximity Read ↗

Targeting ErbB receptor signaling: A pan-ErbB approach to cancerSemantic proximity Read ↗

Neuregulin-1-Mediated Autocrine Signaling Underlies Sensitivity to HER2 Kinase Inhibitors in a Subset of Human CancersSemantic proximity Read ↗

Modulation of Oncogenic NOTCH Signaling in Highly Aggressive Malignancies by Targeting the γ-Secretase Complex: A Systematic ReviewSemantic proximity Read ↗

Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasisSemantic proximity Read ↗

JAK2 regulates paclitaxel resistance in triple negative breast cancersSemantic proximity Read ↗

ErbB2 Induces Notch1 Activity and Function in Breast Cancer CellsSemantic proximity Read ↗

NOTCH Signaling as a Novel Cancer Therapeutic TargetSemantic proximity Read ↗

Anticancer activities of PPARγ in breast cancer are context-dependent.Semantic proximity Read ↗

Intracellular signaling pathways of ErbB2/HER-2 and family membersSemantic proximity Read ↗

The efficacy of CB-103, a first-in-class transcriptional Notch inhibitor, in preclinical models of breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.