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Article

Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and Therapeutics

25 Apr 2019

Abstract excerpt

Breast cancer (BC) is the leading cause of cancer-related mortality in women, only followed by lung cancer. Given the importance of BC in public health, it is essential to identify biomarkers to predict prognosis, predetermine drug resistance and provide treatment guidelines that include personalized targeted therapies. The Hedgehog (Hh) signaling pathway plays an essential role in embryonic development, tissue...

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PMID: 31027259
DOI: 10.3390/cells8040375

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