Article
Mapping of the self-interaction domains in the simian immunodeficiency virus Gag polyprotein.
AIDS research and human retroviruses - 1 Mar 2011
Rauddi María L, Mac Donald Cecilia L, Affranchino José L, González Silvia A
Abstract excerpt
To gain a better understanding of the assembly process in simian immunodeficiency virus (SIV), we first established the conditions under which recombinant SIV Gag lacking the C-terminal p6 domain (SIV GagΔp6) assembled in vitro into spherical particles. Based on the full multimerization capacity of SIV GagΔp6, and to identify the Gag sequences involved in homotypic interactions, we next developed a pull-down...
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