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Article

Hyperphosphorylated truncated protein tau induces caspase-3 independent apoptosis-like pathway in the Alzheimer's disease cellular model.

Journal of Alzheimer's disease : JAD - 1 Jan 2011

Zilkova Monika, Zilka Norbert, Kovac Andrej, Kovacech Branislav, Skrabana Rostislav, Skrabanova Michaela, Novak Michal

Abstract excerpt

Neurofibrillary degeneration and neuronal loss represent key pathological hallmarks of Alzheimer's disease (AD). It has been demonstrated that the decrease of total neuronal numbers correlates with the presence of neurofibrillary degeneration in AD brain. In order to unravel the mechanism leading to the cell death in AD, we developed a stably transfected human neuroblastoma cellular model with...

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Identifiers

PMID: 20966551
DOI: 10.3233/JAD-2010-101434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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