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Article

Tau overexpression inhibits cell apoptosis with the mechanisms involving multiple viability-related factors.

Journal of Alzheimer's disease : JAD - 1 Jan 2010

Wang Hai-Hong, Li Hong-Lian, Liu Rong, Zhang Yao, Liao Kai, Wang Qun, Wang Jian-Zhi, Liu Shi-Jie

Abstract excerpt

The formation of neurofibrillary tangles, mainly composed of hyperphosphorylated tau protein, is a hallmark in the brain of human tauopathies, including Alzheimer's disease (AD). Although neurons bearing neurofibrillary tangles are constantly exposed to various apoptotic stimuli, they do not appe...

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Identifiers

PMID: 20413892
DOI: 10.3233/JAD-2010-091279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20413892-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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