Article
R406W Mutant Tau Protein Conjugated with GFP Aggregates in Cells and Phorbol 12-Myristate 13-Acetate Inhibits Mutant Tau Aggregation and Promotes Neurite Outgrowth in Human Cell Culture Model of Neurodegenerative Diseases
2023-08-11
Abstract excerpt
Patients with neurodegenerative diseases (NDDs) are rapidly increasing all over the world. Alzheimer’s disease (AD), Parkinson’s disease, Huntington’s disease (HD), frontotemporal lobar degeneration (FTLD) and many other diseases are classified as NDDs, however, no therapeutic drugs have been developed against NDDs yet. As common phenomenon, protein oligomers and aggregates (inclusion bodies) are formed in neurons...
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Identifiers and source
- Literature Corpus work
- 4445fb9a-2f31-5553-b9f8-ae454645e50f
- DOI
- 10.20944/preprints202308.0889.v1
