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Article

CNAseg--a novel framework for identification of copy number changes in cancer from second-generation sequencing data.

Bioinformatics (Oxford, England) - 15 Dec 2010

Ivakhno Sergii, Royce Tom, Cox Anthony J, Evers Dirk J, Cheetham R Keira, Tavaré Simon

Abstract excerpt

MOTIVATION: Copy number abnormalities (CNAs) represent an important type of genetic mutation that can lead to abnormal cell growth and proliferation. New high-throughput sequencing technologies promise comprehensive characterization of CNAs. In contrast to microarrays, where probe design follows...

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PMID: 20966003
DOI: 10.1093/bioinformatics/btq587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20966003-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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